公司的核心团队具有资深的基因组专业背景和丰富的行业经验,对相关技术和产业的现状、发展趋势等具有深刻的认识和了解。核心团队成员具有优秀的学术素养,目前已在 NatureScience 等顶尖学术期刊发表多篇学术论文。


团队成员自2007年起开始负责国内首批新一代测序实验平台的搭建,是我国测序平台发展的见证者和骨干力量。安诺优达以此为核心,集合了国内外一大批优秀的高通量测序技术的骨干研发人员,吸引了来自生物学、医学、数学、计算机、物理、化学等不同行业和领域的一流人才,并形成了由博士、硕士和学士等组成的合理人才队伍梯队,共同推动公司的研发和产业快速健康发展。



安诺优达CEO陈重建照片PS000.jpg


陈重建  博士    总裁 


中山大学和法国巴黎十一大学双博士学位,曾在法国居里研究所从事博士后研究,在生物信息、非编码RNA、高通量测序、胚胎干细胞和癌症基因组等领域有丰富的研究经验;曾先后在ScienceDevelopmental CellBioinformaticsRNA Methods等高水平杂志上发表文章;由他开发的多项基因组序列分析与RNA表达分析流程和算法,被学术界广泛引用。2012年陈博士作为海外高层次人才被引进回国,联合创办安诺优达基因科技有限公司,现为公司总裁。 


重建博士近年发表文章PubMed >>

1. Borensztein M, Syx L, Ancelin K, Diabangouaya P, Chen CJ, et al. Xist-dependent imprinted X inactivation and the early developmental consequences of its failure[J]. Nature Structure & Molecular Biology, 2017.

2. Luca Giorgetti, Bryan R. Lajoie, Ava C. Carter, Chong Jian Chen, et al. Structural organization of the inactive X chromosome in the mouse[J]. Nature, 2016.

3. Gendrel AV, Attia M, Chen CJ, Diabangouaya P, Servant N, Barillot E, Heard E. Developmental dynamics and disease potential of random monoallelic gene expression[J]. Dev Cell, 2014, 28(4):366-380. 

4. Leng XM, Diao LT, Li B, Bi YZ, Chen CJ, Zhou H, Qu LH. The ribosomal protein rpl26 promoter is required for its 3' sense terminus ncRNA transcription in Schizosaccharomyces pombe, implicating a new transcriptional mechanism for ncRNAs[J]. Biochem Biophys Res Commun, 2014, 444(1):86-91. 

5. Ciaudo C, Jay F, Okamoto I, Chen CJ, Sarazin A, Servant N, Barillot E, Heard E, Voinnet O. RNAi-dependent and independent control of LINE1 accumulation and mobility in mouse embryonic stem cells[J]. PLoS Genet, 2013, 9(11):e1003791. 

6. Chen CJ, Heard E. Small RNAs derived from structural non-coding RNAs[J]. Methods, 2013, 63(1):76-84. 

7. Chen CJ, Servant N, Toedling J, et al. ncPRO-seq: a tool for annotation and profiling of ncRNAs in sRNA-seq data[J]. Bioinformatics, 2012, 28(23):3147-9. 

8. Servant N, Lajoie BR, Nora EP, Giorgetti L, Chen CJ, Heard E, Dekker J, Barillot E. HiTC: exploration of high-throughput 'C' experiments[J]. Bioinformatics, 2012, 28(21):2843-4. 

9. Chen CJ, liu Q, Zhang YC, Qu LH, Chen YQ, Gautheret D. Genome-wide discovery and analysis of microRNAs and other small RNAs from rice embryogenic callus[J]. RNA Biol, 2011, 8(3):538-547.

10. Chen CJ, Zhou H, Chen YQ, Qu LH, Gautheret D. Plant noncoding RNA gene discovery by "single-genome comparative genomics"[J]. RNA, 2011, 17(3):390-400. 

11. Chen CL, Chen CJ, Vallon O, Huang ZP, Zhou H, Qu LH. Genomewide analysis of box C/D and box H/ACA snoRNAs in Chlamydomonas reinhardtii reveals an extensive organization into intronic gene clusters[J]. Genetics, 2008, 179(1):21-30. 

12. Merchant SS, Prochnik SE, Vallon O, Chen CJ, et al. The Chlamydomonas genome reveals the evolution of key animal and plant functions[J]. Science, 2007, 318(5848):245-250.

13. Huang ZP, Chen CJ, Zhou H, Li BB, Qu LH. A combined computational and experimental analysis of two families of snoRNA genes from Caenorhabditis elegans, revealing the expression and evolution pattern of snoRNAs in nematodes[J]. Genomics, 2007, 89(4):490-501.


 

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